A key component of NeuroQuant^® is the normative database, which provides NeuroQuant^® the capability to compare an individual’s brain structure volume measurements to a healthy population. This allows NeuroQuant^® to deliver a precise indication of where that individual’s brain structure volume lies within an age-and gender-based reference chart, which aids physicians in their assessment of neurodegenerative conditions. This paper provides information on how CorTechs Labs’ normative database was created for NeuroQuant^®.